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Depression may cause neurological alterations in the brain
that result in physical, emotional as well as mental changes. The main causes
of these changes are modifications in the neurotransmitter production such as
norepinepherine and serotonin, and how the neurotransmitter receptor sites
function. Many specialists refer to these changes as being signs of depression.
They may include modifications in loss of appetite, fatigue as well as sleep
patterns.
Stress Hormones
It is very important that you understand the connection
between depression and stress. According to many specialists, chronic stress
and severe acute stress might lead to signs of depression. The effects that it
has physically are compounded by the stress response of the body. During this
stress response, the adrenal glands of the body will secrete three very vital
hormones known as cortisol, norepinephrine and epinephrine. These hormones are
mainly responsible for the symptoms for when the body is in the fight or flight
mode. Blood pressure and elevated heart rate, shunting of blood from organs to
the brain and elevated blood glucose help the body respond to certain threats.
The effects may include loss of appetite, anxiety, irregular and rapid heartbeat
and dry mouth.
Blood Glucose
According to much research,
prolonged depression and stress may affect the production of corticosteroids
which might result into stress hyperglycemia. According to specialists,
hyperglycemia may increase the incidence of poor wound healing, hypertension,
kidney disease and neuropathy.
Immune System
Depression may weaken the body's
immune system, generally the natural killer T-cells that are needed to assist
in protecting the body from cancer-causing agents known as, carcinogens. An
immune system that is weak will also affect the inflammatory response of the
body. Specialists report that this effect from depression has been closely
related with many increased incidents of autoimmune disorders, heart disease,
asthma and osteoarthritis.
Cardiovascular System
According to many specialists from
the American College of Cardiology, due to the releasing of endogenous
catecholamines, also known as the body's stress hormones, this may cause an
increased heart rate as well as vasocontriction. This may lead to an increase
in the body's blood pressure making it necessary for the heart to work much
harder. The common neurovegetative symptoms of stress or depression make it
less likely for an individual to exercise, sleep or even eat properly. These
behaviors will increase the risk of an individual developing a cardiovascular
complication such as stroke, heart attack, atherosclerosis or high blood
pressure.
Mood Changes
It is very common for a person that has depression to feel
helpless and hopeless. Even if there are advantageous events in the
individual's life, their depression will not allow them to improve on their
mood. Another effect that depression has on the emotions is feeling worthless,
in which the patient feels like they should hate themselves and that their life
is worth nothing, not even living. The patient could also experience moments of
feeling guilty, which may be accompanied by crying or sadness spells that have
no real cause. Generally, the person that has depression has a very low level
of mood. Moods that change very frequently could be a sign of depression.
Suicide
When both of these feelings of hopelessness and
worthlessness increase, the patient may become suicidal. It is known that
nearly 15% of the people, who live with depression, generally die from suicide.
If suicidal behaviors or thoughts are common in the individual, it is best that
immediate help is sought. If help is not looked for, the person may cause great
harm to themselves, as causing harm to others isn't typically a symptom of
depression.
Irritability
Another effect on the emotions due to depression is known as
irritability. The person suffering from depression might become more agitated
or irritated, which might be a great change in their emotions when compared
with sadness that is generally associated with those that have depression.
Being annoyed easily is another common symptom associated with depression. The
person could also be found to be restless.
Author Bio:
In this article, Camia Sidle explains the different ways
that depression can ruin the body silently. It is best that if you feel you
have depression, you look into coaching or anger management
counselling that may help you overcome your depression.
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